The Recovery from Grade II Burns in Test Mice (Mus Musculus Linn) After Using Iodine Leaf Latex Gel (Jatropha Multifida Linn)
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Abstract
Burn injuries are emergencies that pose a severe threat and require immediate action to save lives. The saponins, tannins, alkaloids, and flavonoids in iodine leaf latex gel (Jatropha multifida Linn) are known to speed up the healing process for burn wounds. The research aimed to investigate the effect of iodin leaf latex gel on the recovery of grade II burn wounds in male mice (Mus musculus Linn). The research employed a true-experimental laboratory method with-a-post-test-only control design group at the Kusuma Husada University Laboratory in Surakarta. A total of 24 test mice were manipulated and divided into three groups: the positive control group, the negative control group, and the iodine leaf latex gel group. Burn wounds utilized a 1,5 cm superheated mental surface applied to the backs of the mice for 5-10 seconds to induce burn injuries. The observed parameters included the burn wound area, the percentage of burn wound healing, and the duration of burn wound healing. Data analysis operated One-Way ANOVA. The research revealed that iodine leaf latex gel had a restorative time of 8 days and healing percentage of 30,75%. It was better than the other control groups. The statistical analysis indicated significance (<0,05) in the burn wound recovery percentage. In conclusion, a 6% concentration of iodine leaf latex gel had a more favorable effect on burn wound healing than other control groups.
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References
Alepandi, M. et al. (2022) ‘Efektifitas Pemberian Alovera Pada Proses Penyembuhan Luka Bakar’, 2, pp. 15–29.
Anggowarsito, J.L. (2014) ‘Luka Bakar Sudut Pandang Dermatologi’, 2(2), pp. 115–120.
Fajriyani, A. (2022) ‘Pengaruh Simulasi Pelatihan Luka Bakar Derajat II TerhadapKesiapsiagaan Kader Dalam Penanganan Luka Bakar Di Dukuh Kepuh Kelurahan Kunden’, 33, pp. 1–12.
Farid, N. et al. (2020) ‘Formulasi Sediaan Gel Basis HPMC Ekstrak Etanol Daun Jarak Cina (Jatropha multifida) Sebagai Penembuhan Luka Sayat pada Tikus Putih (Rattus norvegicus)’, 1(2).
Febiati, F. (2016) Uji Efektifitas Sediaan Gel Getah Jarak Cina (Jatropha multifida Linn.) Untuk Pengobatan Luka Bakar Pada Tikus Putih (Rattus norvegicus) Jantan Galur Sprague Dawley. Jakarta: Universitas Islam Negeri Syarif Hidayatullah.
Febrianto, R., Farhanah, N. and Sari, E.P. (2016) ‘Hubungan Luka Bakar Derajat Sedang Dan Berat Menurut Kategori American Burn Associstion Dan Faktor-Faktor Yang Mempengaruhi Kejadian Sepsis Di RSUP DR . KARIADI’, 5(4), pp. 1526–1534.
Garg, A. et al. (2002) Spreading of Semisolid Formulation. Update Pharmaceutical Tecnology.
Handayani, F., Sundu, R. and Karapa, H.. (2016) ‘Uji Aktivitas Ekstrak Etanol Biji Pinang (Areca catechu L.) Terhadap penyembuhan Luka Bakar Pada Kulit Punggung Mencit Putih Jantan (Mus musculus)’.
Hardiani, M. (2019) ‘Pengaruh pemberiaan sediaan emulgel chitosan- ekstrak biji pinang Areca catechu .L) Terhadap penyembuhan Luka Bakar Pada Tikus’.
Hermawan, A. et al. (2016) ‘Uji Efektifitas Pohon Yodium ( Jatropha multifida L . ) terhadap Luka pada Mencit ( Mus musculus )”’, 1(2), pp. 1–9.
Nurhayati, K.D. (2021) ‘Pengaruh Pendidikan Kesehatan Dengan Media Poster Terhadap Keterampilan Penanganan Pertama Luka Bakar Di Rumah Tangga Di Dukuh Sapen Kebakkramat’, 000.
Nygaard, R.M. and Endorf, F.W. (2020) ‘Nonmedical Factors Influencing Early Deaths in Burns : A Study of the National Burn Repository’. Available at: https://doi.org/https://doi.org/10.1093/jbcr/irz139.
Pratimasari, D. et al. (2015) ‘Evaluasi sifat fisik dan uji iritasi sediaan salep minyak atsiri bunga cengkeh dalam basis larut air’, 11(1), pp. 9–15.
Rahman, S., Kosman, R. and Amirah, S. (2022) ‘Uji Efek Epitelisasi Ekstrak Batang Wole Woe Asal Kabupaten Halmahera Tengah Terhadap Penyembuhan Luka Bakar Pada Tikus’, As-Syifaa Jurnal Ilmiah , 14(1), pp. 48–56.
Rahmatullah, S., Agustin, W. and Kurnia, N. (2020) ‘Formulasi Dan Evaluasi Sediaan Gel Hand Sanitizer Sebagai Antiseptik Tangan Dengan Variasi Basis Karbopol 940 Dan Tea’, 3(September 2020), pp. 189–194.
Sabandar, C.W. et al. (2013) ‘Phytochemistry Medicinal property , phytochemistry and pharmacology of several Jatropha species ( Euphorbiaceae ): A review’, PHYTOCHEMISTRY [Preprint]. Available at: https://doi.org/10.1016/j.phytochem.2012.10.009.
Santoso, H.B. (2021) Seri Mengenal Tanaman Obat Jarak Tintir. Yogyakarta: Pohon Cahaya Semesta.
Thahir, Z. and Nurfitriah (2018) ‘Uji Efektifitas Penyembuhan Luka Bakar Gel Ekstrak Etanol Daun Jarak Cina (Jatropha multifida ) Pada Kelinci (Oryctolagus cuniculus)’, Nature Methods, 7(6), p. 2016.
Tranggono et al. (2007) Buku Pegangan Ilmu Pengetahuan Kosmetik. Jakarta: Gramedia Pustaka Utama.
Yarsis Septiardi N, Rif Atiningtyas Haris, R.A. (2020) ‘Efektivitas Getah Jarak Cina (Jatropha multifida Linn) Terhadap Proliferasi Luka Pada Tikus Putih Jantan (Sprague dawley)’, Jurnal Ilmu Keperawatan Indonesia (JIKI), 13(1), pp. 46–56.